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«THE PEDIATRIC DIAGNOSTIC EXAMINATION NOTICE Medicine is an ever-changing science. As new research and clinical experience broaden our knowledge, ...»

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THE PEDIATRIC

DIAGNOSTIC

EXAMINATION

NOTICE

Medicine is an ever-changing science. As new research and

clinical experience broaden our knowledge, changes in treatment and drug therapy are required. The authors and the publisher of this work have checked with sources believed to be

reliable in their efforts to provide information that is complete and generally in accord with the standards accepted at

the time of publication. However, in view of the possibility of human error or changes in medical sciences, neither the authors nor the publisher nor any other party who has been involved in the preparation or publication of this work warrants that the information contained herein is in every respect accurate or complete, and they disclaim all responsibility for any errors or omissions or for the results obtained from use of the information contained in this work. Readers are encouraged to confirm the information contained herein with other sources. For example and in particular, readers are advised to check the product information sheet included in the package of each drug they plan to administer to be certain that the information contained in this work is accurate and that changes have not been made in the recommended dose or in the contraindications for administration. This recommendation is of particular importance in connection with new or infrequently used drugs.

THE PEDIATRIC

DIAGNOSTIC

EXAMINATION

Editors Donald E. Greydanus, MD Professor, Pediatrics & Human Development Michigan State University College of Human Medicine Pediatrics Program Director Michigan State University/Kalamazoo Center for Medical Studies Kalamazoo, Michigan Arthur N. Feinberg, MD Professor, Pediatrics & Human Development Michigan State University College of Human Medicine Pediatric Clinic Director Michigan State University/Kalamazoo Center for Medical Studies Kalamazoo, Michigan Dilip R. Patel, MD Professor, Pediatrics & Human Development Michigan State University College of Human Medicine Michigan State University/Kalamazoo Center for Medical Studies Kalamazoo, Michigan Douglas N. Homnick, MD, MPH Professor, Pediatrics & Human Development Michigan State University College of Human Medicine Director, Division of Pediatric Pulmonology Cystic Fibrosis Center Director Pediatrics Program Michigan State University/Kalamazoo Center for Medical Studies Kalamazoo, Michigan New York Chicago San Francisco Lisbon London Madrid Mexico City Milan New Delhi San Juan Seoul Singapore Sydney Toronto Copyright © 2008 by The McGraw-Hill Companies, Inc. All rights reserved. Manufactured in the United States of America. Except as permitted under the United States Copyright Act of 1976, no part of this publication may be reproduced or distributed in any form or by any means, or stored in a database or retrieval system, without the prior written permission of the publisher.

0-07-159354-3 The material in this eBook also appears in the print version of this title: 0-07-147176-6.

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This is a copyrighted work and The McGraw-Hill Companies, Inc. (“McGraw-Hill”) and its licensors reserve all rights in and to the work. Use of this work is subject to these terms.

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DOI: 10.1036/0071471766 Professional

–  –  –

Donald E. Greydanus dedicates this book in loving memory of his parents, John and Margaret Greydanus, and to his loving wife, Katherine, and his wonderful children, Marissa, Elizabeth, Suzanne, and Megan. I am eternally grateful for your love and support. Amor vincit omnia!

Arthur N. Feinberg dedicates this book in memory of his parents, Milton and Rena Feinberg, as the product of their futile attempts to teach him grammar and syntax, and to his wife, Marilyn, and children, Lisa and Daniel, in appreciation of their mutual and unconditional love.

Dilip R. Patel dedicates this book to Ranjan and Neil for their enduring love and support.

Douglas N. Homnick dedicates this book to his wife, Tamara (pediatric nurse), son, Benjamin, daughters, Emily and Hannah, and his parents, Virginia and Myron (pediatrician), whose love and support have always been there. Family (and especially children) has played the most important role in our lives both in and out of the office.

Copyright © 2008 by The McGraw-Hill Companies, Inc. Click here for terms of use.

This page intentionally left blank For more information about this title, click here

–  –  –

Medical Student Reviewer Daniel Olson, BS Fourth Year Medical Student Michigan State University/Kalamazoo Center for Medical Studies Kalamazoo, Michigan Pediatrics Resident Reviewer Elena J. Lewis, MD Pediatric Residency Program Michigan State University/Kalamazoo Center for Medical Studies Kalamazoo, Michigan Medical Illustrator Megan M. Greydanus, BFA Portage, Michigan Authors Jay E. Berkelhamer, MD 2006 President, American Academy of Pediatrics Senior Vice President for Medical Affairs Children’s Healthcare of Atlanta Clinical Professor of Pediatrics Emory School of Medicine Atlanta, Georgia Joseph L. Calles, Jr., MD Clinical Associate Professor of Psychiatry Michigan State University College of Human Medicine Director, Child and Adolescent Psychiatry Psychiatry Residency Training Program Michigan State University/Kalamazoo Center for Medical Studies Kalamazoo, Michigan Joseph D’Ambrosio, DMD, MD Assistant Professor, Internal Medicine and Pediatrics & Human Development Michigan State University College of Human Medicine Transitional Internship Program Director Michigan State University/Kalamazoo Center for Medical Studies Kalamazoo, Michigan ix Copyright © 2008 by The McGraw-Hill Companies, Inc. Click here for terms of use.

x Contributors/Authors Melissa A. Davidson, MD Assistant Professor, Internal Medicine and Pediatrics & Human Development Michigan State University College of Human Medicine Combined Medicine-Pediatrics Program Michigan State University/Kalamazoo Center for Medical Studies Kalamazoo, Michigan Monte A. Del Monte, MD Skillman Professor of Pediatric Ophthalmology Department of Ophthalmology and Visual Science and Pediatrics Professor of Pediatrics Department of Pediatrics and Communicable Diseases Director of Pediatric Ophthalmology and Adult Strabismus W. K. Kellogg Eye Center University of Michigan Ann Arbor, Michigan Martin B. Draznin, MD Professor, Pediatrics & Human Development Michigan State University College of Human Medicine Director, Pediatric Endocrine Division Pediatrics Program Michigan State University/Kalamazoo Center for Medical Studies Kalamazoo, Michigan Arthur N. Feinberg, MD Professor, Pediatrics & Human Development Michigan State University College of Human Medicine Pediatric Clinic Director Michigan State University/Kalamazoo Center for Medical Studies Kalamazoo, Michigan Lisa A. Feinberg, MD Clinical Associate, Department of Pediatric Gastroenterology Cleveland Clinic Foundation Cleveland, Ohio

–  –  –

Renuka Gera, MD Professor and Associate Chair, Department of Pediatrics/Human Development Division of Pediatric and Adolescent Hematology/Oncology Michigan State University College of Human Medicine East Lansing, Michigan Jonathan Gold, MD Assistant Professor, Department of Pediatrics & Human Development Michigan State University College of Human Medicine East Lansing, Michigan Donald E. Greydanus, MD Professor, Pediatrics & Human Development Michigan State University College of Human Medicine Pediatrics Program Director Michigan State University/Kalamazoo Center for Medical Studies Kalamazoo, Michigan Bryan D. Hall, MD Emeritus Professor of Pediatrics Past Chief, Division of Genetics and Dysmorphology Department of Pediatrics, Kentucky Clinic University of Kentucky Lexington, Kentucky Douglas N. Homnick, MD, MPH Professor, Pediatrics & Human Development Michigan State University College of Human Medicine Director, Division of Pediatric Pulmonology Cystic Fibrosis Center Director Pediatrics Program Michigan State University/Kalamazoo Center for Medical Studies Kalamazoo, Michigan Jennifer Johnson, MD Senate emerita Department of Pediatrics University of California, Irvine Irvine, California xii Contributors/Authors Manmohan K. Kamboj, MD Assistant Professor, Pediatrics & Human Development Michigan State University College of Human Medicine Division of Pediatric Endocrinology, Pediatrics Program Michigan State University/Kalamazoo Center for Medical Studies Kalamazoo, Michigan Roshni Kulkarni, MD Professor and Division Chief, Pediatric & Adolescent Hematology/Oncology Director (Pediatric), MSU Center for Bleeding & Clotting Disorders Pediatrics & Human Development Michigan State University College of Human Medicine East Lansing, Michigan;



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