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«3 He a lt h 2 2 Fire 0 3 0 Re a c t iv it y P e rs o n a l P ro t e c t io n Material Safety Data Sheet Phenol, Liquified, neutralized, for molecular ...»


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3 0

Re a c t iv it y

P e rs o n a l

P ro t e c t io n

Material Safety Data Sheet

Phenol, Liquified, neutralized, for molecular biology MSDS

Section 1: Chemical Product and Company Identification

Product Name: Phenol, Liquified, neutralized, for Contact Information:

molecular biology Sciencelab.com, Inc.

14025 Smith Rd.

Catalog Codes: SLP5032 Houston, Texas 77396 CAS#: Mixture.

US Sales: 1-800-901-7247 International Sales: 1-281-441-4400 RTECS: Not applicable.

Order Online: ScienceLab.com TSCA: TSCA 8(b) inventory: Phenol; Water

CHEMTREC (24HR Emergency Telephone), call:

CI#: Not available.

1-800-424-9300 Synonym: Carbolic Acid, Liquified International CHEMTREC, call: 1-703-527-3887 Chemical Name: Carbolic Acid, liquified For non-emergency assistance, call: 1-281-441-4400 Chemical Formula: Not applicable.

Section 2: Composition and Information on Ingredients


Name CAS # % by Weight Phenol 108-95-2 85-100 Water 7732-18-5 0-15

Toxicological Data on Ingredients: Phenol: ORAL (LD50): Acute: 317 mg/kg [Rat]. 270 mg/kg [Mouse]. DERMAL (LD50):

Acute: 630 mg/kg [Rabbit]. 669 mg/kg [Rat].

–  –  –

Potential Acute Health Effects: Very hazardous in case of skin contact (irritant), of eye contact (irritant), of ingestion,.

Hazardous in case of skin contact (corrosive, sensitizer, permeator), of eye contact (corrosive). Slightly hazardous in case of inhalation (lung sensitizer). Non-corrosive for lungs. Liquid or spray mist may produce tissue damage particularly on mucous membranes of eyes, mouth and respiratory tract. Skin contact may produce burns. Inhalation of the spray mist may produce severe irritation of respiratory tract, characterized by coughing, choking, or shortness of breath. Severe over-exposure can result in death. Inflammation of the eye is characterized by redness, watering, and itching. Skin inflammation is characterized by itching, scaling, reddening, or, occasionally, blistering.

Potential Chronic Health Effects: CARCINOGENIC EFFECTS: Classified A4 (Not classifiable for human or animal.) by ACGIH, 3 (Not classifiable for human.) by IARC [Phenol]. MUTAGENIC EFFECTS: Mutagenic for mammalian somatic cells.

[Phenol]. Mutagenic for bacteria and/or yeast. [Phenol]. TERATOGENIC EFFECTS: Not available. DEVELOPMENTAL

–  –  –

Eye Contact: Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at least 15 minutes. Cold water may be used. Get medical attention immediately.

Skin Contact: In case of contact, immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Cover the irritated skin with an emollient. Cold water may be used.Wash clothing before reuse. Thoroughly clean shoes before reuse. Get medical attention immediately.

Serious Skin Contact: Wash with a disinfectant soap and cover the contaminated skin with an anti-bacterial cream. Seek immediate medical attention.

Inhalation: If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention immediately.

Serious Inhalation: Evacuate the victim to a safe area as soon as possible. Loosen tight clothing such as a collar, tie, belt or waistband. If breathing is difficult, administer oxygen. If the victim is not breathing, perform mouth-to-mouth resuscitation. Seek medical attention.

Ingestion: If swallowed, do not induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. Loosen tight clothing such as a collar, tie, belt or waistband. Get medical attention immediately.

Serious Ingestion: Not available.

Section 5: Fire and Explosion Data

Flammability of the Product: May be combustible at high temperature.

Auto-Ignition Temperature: Not available.

Flash Points: The lowest known value is 79 degrees C (174.2 degrees F) (Phenol) Flammable Limits: Not available.

Products of Combustion: These products are carbon oxides (CO, CO2).

Fire Hazards in Presence of Various Substances: Flammable in presence of open flames and sparks, of heat. Nonflammable in presence of shocks, of oxidizing materials, of reducing materials, of combustible materials, of organic materials, of metals, of acids, of alkalis.

Explosion Hazards in Presence of Various Substances: Non-explosive in presence of open flames and sparks, of shocks.

Fire Fighting Media and Instructions: SMALL FIRE: Use DRY chemical powder. LARGE FIRE: Use water spray, fog or foam. Do not use water jet.

Special Remarks on Fire Hazards: COMBUSTIBLE.

Special Remarks on Explosion Hazards: Phenol + sodium nitrite causes explosion on heating. Peroxydisulfuric acid + phenol causes explosion. (Phenol)

–  –  –

Precautions: Keep away from heat. Keep away from sources of ignition. Empty containers pose a fire risk, evaporate the residue under a fume hood. Ground all equipment containing material. Do not ingest. Do not breathe gas/fumes/ vapor/ spray. Never add water to this product. In case of insufficient ventilation, wear suitable respiratory equipment. If ingested, seek medical advice immediately and show the container or the label. Avoid contact with skin and eyes. Keep away from incompatibles such as oxidizing agents, metals, acids, alkalis.

Storage: Keep container tightly closed. Keep container in a cool, well-ventilated area. For short term storage keep refrigerated. Do not store above 8°C (46.4°F). For long term storage before the seal is broken, keep frozen at -20 deg. C (-4 deg. F) or below. Sensitive to light. Store in light-resistant containers.

Section 8: Exposure Controls/Personal Protection

Engineering Controls: Provide exhaust ventilation or other engineering controls to keep the airborne concentrations of vapors below their respective threshold limit value. Ensure that eyewash stations and safety showers are proximal to the workstation location.

Personal Protection: Face shield. Full suit. Vapor respirator. Be sure to use an approved/certified respirator or equivalent.

Gloves. Boots.

Personal Protection in Case of a Large Spill: Splash goggles. Full suit. Vapor respirator. Boots. Gloves. A self contained breathing apparatus should be used to avoid inhalation of the product. Suggested protective clothing might not be sufficient;

consult a specialist BEFORE handling this product.

Exposure Limits: Phenol TWA: 5 (ppm) from ACGIH (TLV) [United States] SKIN TWA: 19 (mg/m3) from ACGIH (TLV) [United States] SKIN TWA: 5 from NIOSH [United States] TWA: 19 (mg/m3) from NIOSH [United States] TWA: 5 (ppm) from OSHA (PEL) [United States] TWA: 19 (mg/m3) from OSHA (PEL) [United States] TWA: 5 (ppm) [Canada] TWA: 19 (mg/m3) [Canada]3 Consult local authorities for acceptable exposure limits.

Section 9: Physical and Chemical Properties

Physical state and appearance: Liquid.

Odor: Sharp, sweet, tangy, medicinal Taste: Not available.

Molecular Weight: Not applicable.

Color: Colorless to light pink pH (1% soln/water): Not available Boiling Point: The lowest known value is 100°C (212°F) (Water).

Melting Point: Not available.

Critical Temperature: Not available.

Specific Gravity: Weighted average: 1.05 (Water = 1) Vapor Pressure: The highest known value is 2.3 kPa (@ 20°C) (Water).

Vapor Density: The highest known value is 0.62 (Air = 1) (Water).

–  –  –

Stability: The product is stable.

Instability Temperature: Not available.

Conditions of Instability: Heat, ignition sources (flames, sparks), incompatible materials Incompatibility with various substances: Reactive with oxidizing agents, metals, acids, alkalis.

Corrosivity: Extremely corrosive in presence of copper. Slightly corrosive in presence of stainless steel(304), of stainless steel(316). Non-corrosive in presence of glass, of aluminum.

Special Remarks on Reactivity: Air and light sensitive. Prone to redden on exposure to light and air. Incompatible with aluminum chloride, peroxydisulfuirc acid, acetaldehyde, sodium nitrite, boron trifluoride diethyl ether + 1,3-butadiene, isocyanates, nitrides, mineral oxidizing acids, calcium hypochlorite, halogens, formaldehyde, metals and alloys, lead, zinc, magnesium and their alloys, plastics, rubber, coatings, sodium nitrate + trifluoroacetic acid. Phenol + isocyanates results in heat generation, and violent polymerization. Phenol + 1,3-butadiene and boron trifluoride diethyl ether complex results in intense exothermic reaction. Phenol + acetaldehyde resultes in violent condensation. (Phenol) Special Remarks on Corrosivity: Minor corrosive effect on bronze. Severe corrosive effect on brass. (Phenol) Polymerization: Will not occur.

Section 11: Toxicological Information

Routes of Entry: Absorbed through skin. Dermal contact. Eye contact. Inhalation. Ingestion.

Toxicity to Animals: Acute oral toxicity (LD50): 292 mg/kg (Mouse) (Calculated value for the mixture). Acute dermal toxicity (LD50): 681 mg/kg (Rabbit) (Calculated value for the mixture).

Chronic Effects on Humans: CARCINOGENIC EFFECTS: Classified A4 (Not classifiable for human or animal.) by ACGIH, 3 (Not classifiable for human.) by IARC [Phenol]. MUTAGENIC EFFECTS: Mutagenic for mammalian somatic cells. [Phenol].

Mutagenic for bacteria and/or yeast. [Phenol]. Contains material which may cause damage to the following organs: kidneys, liver, central nervous system (CNS).

Other Toxic Effects on Humans: Very hazardous in case of skin contact (irritant), of ingestion,. Hazardous in case of skin contact (corrosive, sensitizer, permeator), of eye contact (corrosive), of inhalation (lung corrosive).

Special Remarks on Toxicity to Animals: Lowest Published Lethal Dose: LDL [Human] - Route: Oral; Dose: 140 mg/kg LDL [Infant] - Route: Oral; Dose: 10,000 mg/kg (Phenol) Special Remarks on Chronic Effects on Humans: Animal: passes through the placental barrier. May cause adverse reproductive effects and birth defects (teratogenic) Embryotoxic and/or foetotoxic in animal. May affect genetic material (mutagenic). (Phenol)

Special Remarks on other Toxic Effects on Humans:

–  –  –

DOT Classification: CLASS 6.1: Poisonous material.

Identification: : Phenol solution (Phenol) UNNA: 2821 PG: II Special Provisions for Transport: Not available.

–  –  –

Federal and State Regulations: Connecticut hazardous material survey.: Phenol Illinois toxic substances disclosure to employee act: Phenol Illinois chemical safety act: Phenol New York release reporting list: Phenol Rhode Island RTK hazardous substances: Phenol Pennsylvania RTK: Phenol Minnesota: Phenol Massachusetts RTK: Phenol Massachusetts spill list: Phenol New Jersey: Phenol New Jersey spill list: Phenol Louisiana RTK reporting list: Phenol Louisiana spill reporting: Phenol TSCA 8(b) inventory: Phenol; Water TSCA 4(a) proposed test rules: Phenol TSCA 8(a) IUR: Phenol TSCA 8(d) H and S data reporting: Phenol: effective: 6/1/87; sunset: 6/01/97 SARA 302/304/311/312 extremely hazardous substances: Phenol SARA 313 toxic chemical notification and release reporting: Phenol 92.5% CERCLA: Hazardous substances.: Phenol: 1000 lbs. (453.6 kg);

Other Regulations: OSHA: Hazardous by definition of Hazard Communication Standard (29 CFR 1910.1200).

Other Classifications:

WHMIS (Canada): CLASS D-1A: Material causing immediate and serious toxic effects (VERY TOXIC). CLASS D-2A: Material causing other toxic effects (VERY TOXIC). CLASS E: Corrosive liquid.

DSCL (EEC): R24/25- Toxic in contact with skin and if swallowed. R34- Causes burns. R40- Possible risks of irreversible effects. R43- May cause sensitization by skin contact. R52- Harmful to aquatic organisms. S1/2- Keep locked up and out of the reach of children. S24- Avoid contact with skin. S26- In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39- Wear suitable protective clothing, gloves and eye/face protection. S45- In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible). S46- If swallowed, seek medical advice immediately and show this container or label. S56- Dispose of this material and its container at hazardous or special waste collection point.

HMIS (U.S.A.):

Health Hazard: 3 Fire Hazard: 2 Reactivity: 0

Personal Protection:

National Fire Protection Association (U.S.A.):

–  –  –

References: Not available.

Other Special Considerations: Not available.

Created: 10/10/2005 11:17 AM Last Updated: 05/21/2013 12:00 PM The information above is believed to be accurate and represents the best information currently available to us. However, we make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assume no liability resulting from its use. Users should make their own investigations to determine the suitability of the information for their particular purposes. In no event shall ScienceLab.com be liable for any claims, losses, or damages of any third party or for lost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if ScienceLab.com has been advised of the possibility of such damages.

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