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«Calendar Monday, September 29 Department of Physiology Cancer Faculty Candidate Seminar: Explore novel epigenetic targets for breast cancer therapy. ...»

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The BMB Weekly Vol. 41, No. 40, September 29-October 3, 2008

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Please send submissions to: Katie Gallagher at galla134@msu.edu or 105B Biochemistry (mailbox on 2 floor)

Calendar

Monday, September 29

Department of Physiology Cancer Faculty Candidate Seminar: Explore novel epigenetic targets for breast

cancer therapy. Yi Huang, Johns Hopkins University, 9:00 a.m., 1425 Biomedical and Physical Sciences.

Chemistry Seminar: Presentation by Kapil Lokare, Michigan State University, 11:20 a.m., 136 Chemistry.

Entomology Seminar: Thirty years in the outdoor classroom – entomology and the study abroad program. Larry Besaw, Michigan State University, 4:00 p.m., 204 Natural Science.

Physics and Astronomy Seminar: Learning about quantum measurements using superconducting devices. Frank Wilhelm, University of Waterloo, 4:10 p.m., 1400 Biomedical and Physical Sciences.

Plant Biology and Plant Research Lab Seminar: Genetics and evolution of flower color. Mark Rausher, Duke University, 4:10 p.m., 101 Biochemistry.

Tuesday, September 30 Statistics and Probability Seminar: Minimum distance estimation of the error distribution in multivariate regression and GARCH models. Mervyn J. Silvapulle, Monash University, 10:20 a.m., A-405 Wells Hall.

Plant Research Laboratory Seminar: Characterization of subcellular localization and function of HopM1 and AtMIN7 in Arabidopsis thaliana. Young Nam Lee, 12:00 noon, 168 Plant Biology.

Physics and Astronomy Seminar: Presentation by Tom Flacke, University of Michigan, 1:50 p.m., 1400 Biomedical and Physical Sciences.

Microbiology and Molecular Genetics Seminar: Legionella pneumophila, a pathogen in search of its next meal.

Michele Swanson, University of Michigan, 4:10 p.m., 1415 Biomedical and Physical Sciences.

Wednesday, October 1 First Deferred Payment Due for Fall Semester Pharmacology and Toxicology Seminar: Brody Lecture Series: Presentation by Kenneth P. Minneman, Emory University, 12:00 noon, B448 Life Sciences.

Josh Kwekel Doctoral Dissertation: Comparative toxicogenomic analysis of estrogen and o,p’-DDT-induced uterotrophy across rodent species. 2:00 p.m., 162 Food Safety and Toxicology.

Chemistry Seminar: Presentation by Dalila Kovacs, Grand Valley State University, 3:00 p.m., 136 Chemistry.

Ecology, Evolutionary Biology, and Behavior Program Seminar: EEBB Distinguished Lecture: The cognitive representation of social structure in animals. Alan B. Bond, University of Nebraska, 3:30 p.m., 247 Plant Biology.

BMB Graduate Student Forum: Presentation by Hui Yang, Hegg Lab, 4:30 p.m., 208 Biochemistry.

Calendar continued Wednesday, October 1 The Graduate School: Developing Your Written Credentials: CV’s, Resumes, and More. 5:00-6:30 p.m., Room 6, Student Services Building. For more information, visit http://grad.msu.edu/prep/eveningworkshops.htm#developing.

Thursday, October 2 CNS Faculty Development Seminar: This seminar is for pre-tenure and fixed-term faculty along with teaching mentors. The seminar discussion will be on preparing a teaching or course portfolio for promotion and/or tenure.

Dean Duncan Sibley, 8:00 a.m., 1400 Biomedical and Physical Sciences.

Biochemistry and Molecular Biology Seminar: Quorum sensing in vibrio cholerae. Bonnie Bassler, Princeton University, 11:30 a.m., 101 Biochemistry.

Ecology, Evolutionary Biology, and Behavior Program Seminar: EEBB Distinguished Lecture: List-linking and other impossibly difficult tasks. Alan B. Bond, University of Nebraska, 12:00 noon, 203C Natural Science.

Neuroscience Seminar: The effects of obesity and hypertension on the cerebral vasculature and acute ischemic stroke. Anne Dorrance, Michigan State University, 12:30 p.m., 1425 Biomedical and Physical Sciences.

Geological Sciences Seminar: Distinguished Lecturer Series: Exploring oceanic magmatism through the study of silicate melt inclusions. Adam Kent, Oregon State University, 4:00 p.m., 204 Natural Science.

Chemistry Seminar: Presentation by Haw Yang, 4:10 p.m., 136 Chemistry.

Physics and Astronomy Seminar: Presentation by Don Eigler, IBM Almaden Research Center, 4:10 p.m., 1415 Biomedical and Physical Sciences.

The Graduate School: Creating a teaching philosophy you can use, Part I: Establishing the basics. 5:30-7:00 p.m., Spartan Room C, International Center. Visit http://tap.msu.edu/workshops/2008/sep.htm#091808 for more information.

Friday, October 3 Science at the Edge: Quantitative Biology/Gene Expression in Development & Disease Seminar: Functional genomics of yeast stress defense. Audrey Gasch, University of Wisconsin-Madison, 11:30 a.m., 1400 Biomedical and Physical Sciences.

Department of Pathobiology and Diagnostic Investigation Seminar: Diseases of zoonotic importance: An Indian perspective. L Gunaseelan, Madras Veterinary College, 12:00 noon, 101 Diagnostic Center for Population and Animal Health.

Chemistry Seminar: Small volume sampling in biological systems: Recent developments in microdialysis and comparable techniques. Steve Halpin, Michigan State University, 12:40 p.m., 136 Chemistry.

Published Articles T. Ventriglia, M. A. Ballicora, M. Teresa Ruíz, M. R. Pedro, F. Valverde, J. Preiss and José M. Romero. (2008) Evolutionary fate of ADP-glucose pyrophosphorylase gene family in Arabidopsis thaliana. Plant Physiol. 148: 65-76.





Faculty Accomplishments McGroarty and Wilcox Awarded $3.98M NSF Advance Grant: Estelle McGroarty, assistant vice president, VPRGS; assistant vice provost, LCT; and professor of biochemistry and molecular biology is part of a team that was recently awarded a $3.98M Advance Grant from the National Science Foundation. The five year project, for which McGroarty is the lead co-principal investigator with principal investigator, Provost Kim Wilcox, is titled "Advancing Diversity through Alignment of Policies and Practices (ADAPP)."

The goal of the ADAPP project is to develop systemic approaches to increase the representation and advancement of women in academic science and engineering careers, thereby contributing to the development of a more diverse science and engineering workforce. The initiative focuses on recruitment and advancement policies and practices in the Colleges of Engineering, Natural Science and Social Science, with the intent that changes shown to be effective will be applied to the whole University.

Burton and Nedialkov Contribute to Major Molecular Cell Publication: Zachary Burton, professor of biochemistry and molecular biology, and his associate Yuri Nedialkov contributed to a major paper, published in Molecular Cell, that describes the role of active site closing by RNA polymerase II in the fidelity of transcription. “Fidelity” is making the correct (DNA template specified) bond rather than an incorrect bond.

"Transient reversal of RNA polymerase II active site closing controls fidelity of transcription elongation," authored by Kireeva ML, Nedialkov YA, Cremona GH, Purtov YA, Lubkowska L, Malagon F, Burton ZF, Strathern JN, and Kashlev M. may be found at Mol Cell. 2008 Jun 6;30(5):557-66.

Pamela J. Fraker inducted into the National Academy of Sciences: Pamela J. Fraker, professor of biochemistry and molecular biology and of food science and human nutrition, was inducted into the National Academy of Sciences this April. Considered one of the highest honors accorded a U.S. scientist, academy membership recognizes distinguished and continuing achievements in original research.

Fraker, known for her discoveries of the impact of nutritional deficiencies, particularly of zinc, on immune defense, is the first woman from Michigan State University to receive this honor.

Dr. Fraker is shown here with the "Registry of Membership" which all inductees sign.

Founded by Abraham Lincoln, the registry includes the signatures of such noted scientists as Thomas Edison and Albert Einstein.

For more information about the National Academy of Sciences, see http://www.nationalacademies.org/memarea/ Yogesh Saini article accepted by JBC: Yogesh Saini, doctoral candidate in LaPres lab, has had an article accepted by the Journal of Biological Chemistry. "HIF1alpha is essential for normal intrauterine differentiation of alveolar epithelium and surfactant production in the newborn lung of mice," authored by Yogesh Saini, Jack R. Harkema, and John J. LaPres may be viewed in the JBC online. See article" A. Dan Jones Invited Speaker at Metabolomics Society's 4th International Conference: A.

Dan Jones, professor of biochemistry and molecular biology, and directory of MSU's Mass Spectrometry Facility, gave an invited talk September 3 at the Metabolomics Society's 4th International Conference in Boston in September. The talk was part of a workshop to guide investigators toward more efficient and robust, and less costly procedures for both targeted and comprehensive profiling of metabolites.

Faculty Accomplishments continued Pauly Designs World's First Biomass Analysis Robot: Markus Pauly, associate professor of biochemistry and molecular biology, has designed the world’s only biomass analysis robot, iWall, to efficiently process samples needed in the research for biofuel creation. (See iWall in action) In order to determine which plants and trees yield large amounts of sugars that can be converted into biofuel, researchers must grind hundreds (sometimes thousands) of plant material samples into a fine powder to measure the same small amount into test vials. The iWall will enable what was a mind-numbing task, done by hand with mortar and pestle, to be done in less time and with more precision.

"The robot can grind, weigh and dispense 350 samples a day in one run," Pauly explained. Done by hand, the same amount of work requires 16 hours of tedious labor.

The iWall robot was built to Pauly's specifications by Labman Automation, a British company. "I started asking around to see if we could get a machine to do this and I was told that no machine existed," Pauly said. "The GLBRC grant allowed us to have this one built. It's going to be a great tool for all the GLBRC researchers and other MSU biochemists. The advantage is that it can do hundreds of different kinds of samples in one run."

Pauly leads the analytic group of the Great Lakes Bioenergy Research Center. The GLBRC is a partnership between MSU and the University of Wisconsin-Madison working to solve the complex problems in converting renewable materials into energy.

For more on the iWall, and GLBRC open house, please see: http://www.bioeconomy.msu.edu/news/iWall.aspx Announcements Graduate Minority Women’s Support Group: The focus of this group is to assist minority women in traversing the academic and social pressures involved with being a graduate student.

Open to all graduate women with minority status (e.g., race, ethnicity, sexual orientation, religion, disability). This group meets every Tuesday from 5:00 - 6:30 pm in 224 Student Services Building and will begin on September 9, 2008. *Pre-group interview is required.

Please contact Dr. Tawa Sina at 355-8270 if interested in participating.

LaTeX document preparation system introduction and instruction: Special Course Announcement, Spring 2009: Offered by Dr. Cliff Weil, MSU Mathematics. LaTeX is a document preparation system for high-quality typesetting. It is most often used for technical or scientific documents, including thesis formatting. LaTeX is not word processing software. The seminar will meet once a week beginning the first week of the semester. It may be taken for one credit or just audited. If you are interested in participating in any of Dr. Weil's offerings, please contact him directly at 353-8489 or email weil@math.msu.edu.

The Graduate School: Responsible Conduct of Research Series: Maintaining a productive and responsive environment for conducting graduate research. Wednesday, October 15th, 6:00-8:00 p.m., Big Ten C, Kellogg Hotel and Conference Center. For more information, please visit http://grad.msu.edu/all/respnov.htm. Registration is required. To register, please send an e-mail to gradwrsp@msu.edu and include your name, department, e-mail address, and the name of the session you wish to attend.

The Graduate School: Developing Communication and Conflict Management Skills to Save Time and Enhance Productivity. Friday, October 17th, 9:00 a.m. – 2:30 p.m., Room 6, Student Services Building. For more information, please visit http://grad.msu.edu/pdf/conflictoct08.pdf. Registration is required. To register, please send an e-mail to gradwrsp@msu.edu and include your name, department, e-mail address, and the name of the session you wish to attend.

Announcements continued The Graduate School: Navigating the PhD: A Writing Workshop: This is a two-part workshop series. The series is targeted to doctoral students in the early stages of their graduate program. The titles of the parts are: Part 1: Demystifying the Dissertation, Personal Management, Forming Committees, Working with Committees, & Comprehensive Exams;

Part 2: Topics and Proposals, Writing Strategies, Revision Strategies, The Defense...and Beyond, & Graduate Writing Groups. Each part will be limited to 30 doctoral students. Although it is highly recommended that you attend both parts, you may register for only one part. Lunch will be served during the sessions. This workshop series is offered every semester. Registration is required. To register, please send an email to gradwrsp@msu.edu and include your name, phone number, email address, and department.

Part 1: Saturday, October 20, 2008 Part 2: Saturday, November 10, 2008 9:00 a.m. – 3:00 p.m.

The Writing Center, 300 Bessey Hall Position Vacancies (copies of notices are in maroon binder in Room 302A) A tenure-track assistant professor position is available in the Department of Microbiology at the University of Massachusetts Amherst. They are seeking applicants with demonstrated experience in, but not limited to, Microbial Genetics. The department is especially interested in applicants studying prokaryotic or eukaryotic model sytems that are pathogenic or medically important. Review of applications will begin October 6, 2008 and continue until the position is filled. For more information about the department, please visit http://www.bio.umass.edu/micro/.



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